Neutron capture therapy with a new boron-porphyrin compound in the rat 9L glioma model.

نویسندگان

  • Y Shibata
  • A Matsumura
  • T Yamamoto
  • K Nakagawa
  • Y Yoshii
  • T Nose
  • I Sakata
  • S Nakajima
  • Y Hayakawa
  • K Ono
چکیده

Neutron capture therapy with a new boron-porphyrin compound was tested in a rat brain tumor model. Although the concentration of boron in the tumor was too low to elicit a therapeutic effect, prominent histopathologic changes, such as necrosis, congestion and bleeding were observed in the tumors of the rats which were administered the boron neutron capture therapy.

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عنوان ژورنال:
  • Journal of experimental & clinical cancer research : CR

دوره 17 3  شماره 

صفحات  -

تاریخ انتشار 1998